Primary Cell Culture Scientist

Cambridge, Massachusetts

Company Description

Job Description

The Global Investigative Toxicology team is a cross-functional team of scientists that aim to detect and de-risk toxicity in Client's portfolio to help make medicines safer and more effective. We are looking for a Research Associate Scientist to support these efforts across platforms and modalities. The Research Associate Scientist will contribute ideas and deliver decision-making data to inform project teams on improved efficacy and/or de-risking of potential toxicities.

  • Work as part of a global team of safety assessment scientists to detect and de-risk toxicities associated client's assets.
  • Design and implement early safety assessment screening strategies to enable the progression of optimized therapeutic candidates.
  • Conduct cell-basedin vitroassays to characterize toxicities for medicines in discovery & development.
  • Develop novelin vitromodel systems to assess safety risks associated client's assets.
  • Develop, design, execute, and interpretin vitrocell-based assays to characterize diverse mechanisms of toxicity.
  • Maintain cultures of immortalized tumor cell lines, primary cell types of various origin (lung, liver, kidney, intestine, pancreas, blood etc.) with primary focus being on primary CD34+ cells and differentiating CD34+ cells to various cell types.
  • Prepare experimental protocols, analyze experimental data, and present study results in team and department meetings.
  • Contribute ideas to drive innovation within investigative toxicology and with key collaborators (e.g. pharmacology, DMPK, bioinformatics).
  • Good documentation practices are required.


    • Ph.D. with 0-1 years or MS. with 3+ years or BS with 5+ years of experience in biology, biochemistry, pharmacology, or a related discipline.
    • Expert with standard aseptic cell culture technique, including experience culturing various tumor cell lines and primary cells. Experience with culturing and differentiating CD34+ cells is a plus.
    • Broad experience with cell-based functional assays. Experience with cell transfection/transduction, imaging, and flow cytometry is a plus.
    • Basic experience with molecular biology techniques including RNA/DNA extraction, qPCR, western blot
    • Experience working in a matrixed team environment at a pharmaceutical company and/or CRO.
    • Broad scientific knowledge in hematology, immunology, and pharmacology.
    • Self-motivated with strong time management and organizational skills.

    Additional Information

    Position is full-time, Monday - Friday 8:00am - 5:00pm.Candidates currently living within a commutable distance of Cambridge, MAare encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.
    • Life and disability insurance
    • 401(k) with company match
    • Paid vacation and holidays

    Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

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