Principal Scientist / Medicinal Chemistry leader, Oncology Chemistry

Waltham, Massachusetts

This job has expired.

Principal Scientist / Medicinal Chemistry leader, Oncology Chemistry

Location: Waltham, US

Are you a highly motivated Principal Scientist with expertise in Medicinal Chemistry and a passion to work in Oncology?

At AstraZeneca Oncology, we are not afraid to do things differently. Our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives. Our mission is to make a meaningful difference to human health through great medicines that benefit patients in need, and add value to society. We discover, develop, manufacture and market prescription medicines for important areas of healthcare, which include some of the world's most serious illnesses: cancer, cardiovascular disease, respiratory, inflammation, and autoimmune diseases. We are driven by a shared goal to make a positive impact on the lives of patients with these serious diseases.

Oncology R&D is a core therapeutic area and growth platform at AstraZeneca. Our vision is to be at the forefront of developing the next generation of cancer therapies. We work together across global boundaries to have a positive impact in the world by solving challenging scientific problems!

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals. We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health. Does this sound like a team you would like to join?

About The Site

The Waltham R&D site is home to our small-molecule oncology research in North America, and is situated within a biopharma cluster of academic research institutions, medical centers, pharmaceutical companies and biotech startups. The Boston region is consistently ranked #1 globally for biotech research, investment, talent recruitment and lab space.

The campus, also known as the Boston BioHub, is one of the largest and most dynamic life-science research hubs in the region. It is home to more than 800 scientists and technical specialists working in nine different pharmaceutical and biotech companies. The site is also home to the AstraZeneca Incubator, a program that helps emerging companies advance novel and innovative healthcare solutions to meet the needs of patients. Plenty of free parking, with charging stations now available for electric vehicles, and shuttle service to local transportation hubs.

Main Duties and Responsibilities

We are seeking to recruit a Principal Scientist Medicinal Chemistry leader in the Oncology Chemistry group in Waltham, MA. In this role, you will provide scientific leadership, including directly lead specific project(s), be a global scientific influencer, and serve as a mentor to less experienced scientists.

You will be accountable for:

  • Driving the strategic direction of the project(s) assigned in alignment with the portfolio priorities
  • Ensuring the timely delivery of key activities and project milestones by working closely across functions
  • Working globally within Oncology Chemistry department to drive a global community of practice model to accelerate project delivery
  • Communicating optimally with senior leadership
  • Providing scientific mentorship to junior medicinal chemists

Essential Requirements:
  • Ph.D. in organic chemistry with >8 years of research experience, or BS/MS in chemistry with >15 years of research experience within the pharmaceutical industry
  • 'Pioneering' knowledge of medicinal chemistry theories, methodologies and practices, and their applications in small molecule drug discovery, from target identification to development candidate delivery
  • Robust track record of portfolio delivery, with proven examples of leading a team to tackle medicinal chemistry challenges by driving strategies and innovation
  • Excellent cross-functional knowledge and team-working skills, and ability to represent chemistry in cross-disciplinary discussions
  • Effective organizational, communication, interpersonal skills with the flexibility to accommodate programmatic changes and/or scientific directions.
  • Strong track record of leading, motivating, developing a team of highly qualified personnel
  • Strong record of recent peer-reviewed publications and/or external presentations and engagement in the external scientific community.

Desirable Experience:
  • Strategic contribution to scientific and/or business initiatives within biotech/pharma industry.
  • Track record of working with external partners
  • Experience with novel medicinal chemistry modalities
  • Experience with small molecule drug discovery within oncology

Next Steps - Apply today!

So, what's next

If you are inspired by the possibilities, don't hesitate in submitting an application today

Closing date: 13th May 2022

Competitive Remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package

Where can I find out more

Our Social Media, Follow AstraZeneca on LinkedIn

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To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants. COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.

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