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Overview
St. Jude is developing a comprehensive effort to study the immune system in cancer patients, with particular applications aimed at developing and refining immunotherapy approaches. For this effort, bioinformatics is critical, and we are actively searching for a highly motivated scientist who will serve as an informatic bridge between the Departments of Immunology and Bone Marrow Transplant & Cellular Therapy. In addition to spanning these two departments, you will be part of the Thomas Lab and will report to the Director of Immunoinformatics. Working alongside other bioinformaticians, clinicians, and staff scientists, you will have numerous opportunities to be involved in cutting-edge immunological research with direct translational applications, including analysis of near real-time data obtained from ongoing clinical trials. This work will in part entail the development, evaluation, and utilization of novel analytical tools related to bulk and single-cell expression and epigenetic analyses, including processes related to data processing, statistical analysis, network analysis, and data visualization; as such, this is a prime opportunity to develop expertise in the burgeoning field of single-cell bioinformatics broadly and in areas of cancer immunotherapy specifically.Experience in R is required, and previous experience analyzing single-cell gene expression data is highly desirable but not required. Experience with general-purpose programming languages (C/C++, JavaScript, or PHP) preferred but not required. Background in molecular biology, cell biology, immunology, and/or cancer biology, wetlab environment, and familiarity with next-generation sequence analysis are highly preferred. Ability to effectively multitask and communicate clearly are both integral to success in this position.
Responsibilities
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